Monday, May 26th
Monday, May 26th
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1.30 – 2.30 PM Registration
2.30 – 3.00 PM Opening ceremony
Greetings of the Authorities
Dr. Alessandro Canelli, Mayor
Prof. Menico Rizzi, Rector
Ing. Stefano Scarpetta, General Director of the University-Hospital
Prof. Dr. Renzo Boldorini, Head of the School of Medicine
Prof. Dr. Lia Rimondini, Head of DISS
Prof. Dr. Gianluca Aimaretti, Head of DIMET
Prof. Dr. Gianluca Gaidano, Pro-Rector
Prof. Dr. Ciro Isidoro, Head of the conference
3.00 – 6.15 PM 1st Session Chairs: Camelia Munteanu - Riccardo Moia
3.00 - 3.30 PM
Title: (KL) The Long Game of lncRNAs: Navigating Signatures, Circuits, and Therapeutic Targets in Ovarian Cancer
Danny N. Dhanasekaran
The University of Oklahoma Health Sciences Center, USA
3.30 - 3.55 PM
Title: (IL) Cancer Chemoprevention and Biomarkers
Jianyu Rao
University of California, USA
3.55 - 4.20 PM
Title: (IL) Mitochondrial Dysfunction and Energy Crisis in Cancer Cachexia: Relevance of the Tumor Host Cross-talk
Paola Costelli
Università degli Studi di Torino, Italy
4.20 - 4.45 PM
Title: (IL) Adaptation of Chronic Lymphocytic Leukemia to Ibrutinib is Mediated by Epigenetic Plasticity of Residual Disease and by-pass Signaling via MAPK Pathway
Lodovico Terzi di Bergamo
Università della Svizzera Italiana, Switzerland
4.45 - 5.15 PM
Title: (KL) CD49d-expressing CLL: Clinical and Biological Features
Valter Gattei
Centro di Riferimento Oncologico di Aviano, Italy
5.15 - 5.40 PM
Title: (IL) TGS1 Mediated mRNA 5’-cap Trimethylation Promotes Oxidative Phosphorylation in Acute Myeloid Leukaemia
Isaia Barbieri
Università di Torino, Italy
5.40 - 5.55 PM
Title: (OC) Jagged Ligands on Extracellular Vesicles Drive Osteoclast Formation in Multiple Myeloma
Domenica Giannandrea
Università degli Studi di Milano, Italy
5.55 - 6.10 PM
Title: (OC) Clonal Hematopoiesis in Follicular Lymphoma, Analysis of the phase III FIL FOLL12 trial
Nawar Maher
Università del Piemonte Orientale, Italy
6.10 - 6.15 PM
Title: (FC) Immunoglobulin Light Chain Mutational Status Refines IGHV Prognostic Value in Identifying Chronic Lymphocytic Leukemia Patients with Early Treatment Requirement
Bashar AI Deeban
Università del Piemonte Orientale, Italy
6.15 – 7.15 PM Welcome party
Social event - Aperitivo Buffet
7.30 PM Classical music concert and Apericena buffet (by invitation ONLY)
Social event at Conservatorio "Guido Cantelli"
Tuesday, May 27th
Tuesday, May 27th
8.30 – 11.00 AM 2nd Session Chairs: Devrim Gozuacik - Alessandra Ferraresi
8.30 - 8.45 AM
Title: (OC) CD274/PD-L1 Promoter Hypomethylation in Non-small Cell Lung Cancer
Federico Pio Fabrizio
University of Enna "Kore", Italy
8.45 - 8.50 AM
Title: (FC) Clinical Impact of Untargeted Baseline Plasma Metabolomics in Newly Diagnosed Diffuse Large B Cell Lymphoma
Luca Cividini
Università del Piemonte Orientale, Italy
8.50 - 8.55 AM
Title: (FC) Cancer Cell-derived Factor VIII Plays a Direct Role in Cancer Pathophysiology
Ali Fawaz
Università del Piemonte Orientale, Italy
8.55 - 9.25 AM
Title: (KL) Abscopal anti-tumoral effect of COVID-19 mRNA Vaccination
Guido Ferlazzo
Università degli Studi di Genova, Italy
9.25 - 9.48 AM
Title: (IL) Tyrosine Kinase Inhibitor Induces Changes in the 3D Genome Organization of Lung Cancer Cells Leading to Expression of Tumor Suppressor Genes
Guillermo Barreto
Université de Lorraine, France
9.48 - 10.03 AM
Title: (OC) Obesity-Cancer Nexus: Targeting LncRNAs in Adipocyte-Ovarian Cancer Cell Crosstalk
Camelia Munteanu
University of Agricultural Sciences and Veterinary Medicine Cluj Napoca, Romania
10.03 - 10.11 AM
Title: (SC) Unveiling a Novel Metabolic Vulnerability in Lung Adenocarcinoma: Targeting OADHC for Improved Therapy and Immune Response
Roberta Basile
Università del Piemonte Orientale, Italy
10.11 - 10.19 AM
Title: (SC) The Effect of Oxidative Stress on Extracellular Vesicle-Mediated Communication in Multiple Myeloma
Giulia Sauro
Università degli Studi di Milano, Italy
10.19 - 10.27 AM
Title: (SC) Modulation of Cathepsin D Expression Influences Neuroblastoma Cell Growth in both 2D and 3D Cultures in Response to EGF: Implications for the Metastatic Process
Chiara Lualdi
Università del Piemonte Orientale, Italy
10.27 - 10.35 AM
Title: (SC) Sirt1 Targeting as a Potential Radio-Sensitizing Strategy in HPV-associated Cancer
Carlo Girone
Università del Piemonte Orientale, Italy
10.35 - 10.50 AM
Title: (OC) Therapeutic Effect of Medicinal Plants in the Treatment of Leukemia
Sara Damiano
Università di Napoli Federico II, Italy
10.50 - 10.55 AM
Title: (FC) Lung Cancer Cells Respond to Pro-Differentiation Media and Downregulate Cancer Stem Cell Features
Alice Grossi
Università di Pavia, Italy
10.55 - 11.00 AM
Title: (FC) One Reaction, Countless Degraders: A Versatile Platform for the Synthesis of PROTACs and HyTags for Cancer Therapy
Laura Gioiello
Università del Piemonte Orientale, Italy
11.00 – 11.30 AM Coffee break
11.30 AM – 1.30 PM 3rd Session Chairs: Matteo Donadon - Arnold Stern
11.30 AM - 12.00 PM
Title: (KL) Discovery of Molecular Regulators of Autophagy and Implications for Cancer
Devrim Gozuacik
Koç University, Turkey
12.00 - 12.15 PM
Title: (OC) CYP4s Inhibitors in Oncology: Targeting Cancer Stem Cells with Isocyanide Derivatives
Gian Cesare Tron
Università del Piemonte Orientale, Italy
12.15 - 12.20 PM
Title: (FC) Preliminary Effects of Stilbenes and Cisplatin Co-Treatments on Human Lung Adenocarcinoma Cell Line
Mattia De Vita
Università di Pavia, Italy
12.20 - 12.25 PM
Title: (FC) Disruption of Sodium Homeostasis as a New Anticancer Strategy for Hepatocellular Carcinoma (HCC): Studies Employing Primary Hepatocytes, HCC Cells and in vivo Models of HCC Allograft and of NAFLD-DEN induce Hepatocarcinogenesis
Simone Fiorilla
Università del Piemonte Orientale, Italy
12.25 - 12.40 PM
Title: (OC) Boric acid and Serotonin combination destroys the DNA Double-strand break repair process of Lung Cancer Stem Cells
Tugba Semerci Sevimli
Eskisehir Osmangazi University, Turkey
12.40 - 1.04 PM
Title: (IL) Extracellular Matrix Dynamics and Colorectal Liver Metastasis: Insights from Organ Bioengineering
Andrea Peloso
Hôpitaux Universitaires de Genève, Switzerland
1.04 - 1.12 PM
Title: (SC) Metabolic Reprogramming of Anoikis-Resistant Melanoma Cells
Silvia Peppicelli
Università degli Studi di Firenze, Italy
1.12 - 1.20 PM
Title: (SC) Acute Myeloid Leukemia: a Key Role of DGKα and DGKζ in Cell Viability
Elisa Gorla
Università del Piemonte Orientale, Italy
1.20 - 1.25 PM
Title: (FC) Analysing Metabolic Pathways Involved in Cis-Platin Resistance of Head and Neck Squamous Cell Carcinoma
Nicole Edel
Max-Delbrück-Centrum für Molekulare Medizin, Germany
1.25 - 1.30 PM
Title: (FC) Exploring the Impact of Extracellular Nicotinamide Phosphoribosyltransferase (eNAMPT)-Activated Pericytes in Breast Cancer Progression
Marianna Moro
Università del Piemonte Orientale, Italy
1.30 – 2.30 PM Lunch
2.30 – 7.10 PM 4th Session Chairs: Tugba Semerci Sevimli - Guillermo Barreto
2.30 - 2.45 PM
Title: (OC) Metabolic Vulnerabilities in Pancreatic Cancer: Exploring Nutrient Sensing and Mitochondrial Adaptations
Miriam Martini
University of Torino, Italy
2.45 - 3.08 PM
Title: (IL) Decoding Cancer Metabolic Networks and Drug Targets Using Time and Isotope Resolved Metabolomics
Stefan Kempa
Max-Delbrück-Centrum für Molekulare Medizin, Germany
3.08 - 3.32 PM
Title: (IL) Rewiring of Lipid Metabolism in Drug-Resistant Lung Cancer Cells
Joanna Kopecka
Università di Torino, Italy
3.32 - 3.40 PM
Title: (SC) Metabolic Mechanisms of Prostate Cancer Resistance to Glutamine Depletion
Giuseppe Taurino
Università di Parma, Italy
3.40- 3.55 PM
Title: (OC) Multiomic Characterization of Intrahepatic Cholangiocarcinoma
Riccardo Sinella
Università del Piemonte Orientale, Italy
3.55 - 4.10 PM
Title: (OC) Tackling Novel Metabolic Vulnerabilities to Hamper Glioma Stem Cells Growth: The Role of the V-ATPase Proton Pump
Alessandra Maria Storaci
Università degli Studi di Milano, Italy
4.10 - 4.25 PM
Title: (OC) New Strategies in the Treatment of Melanoma
Roberta Cassano
Università della Calabria, Italy
4.25 - 4.40 PM
Title: (OC) Avatars in Personalized Medicine of Pancreatic Adenocarcinoma. Lights and Shadows of Human Primary Cell Cultures in the Creation of Preclinical Models
Niccola Funel
University of Pisa, Italy
4.40 - 4.54 PM
Title: (OC) NKX3-2 Promotes Ovarian Cancer Cell Migration by HDAC6-mediated Repositioning of Lysosomes and Downregulation of Autophagy
Alessandra Ferraresi
Università del Piemonte Orientale, Italy
4.54 - 5.02 PM
Title: (SC) MiR-214 Drives Metabolism Rewiring in Melanoma by Regulating Proteins Involved in the Endoplasmic Reticulum-Mitochondria Axis
Andrea Scircoli
Università di Torino, Italy
5.02 - 5.10 PM
Title: (SC) Aquaporin 1, 8, and 9 Expression on Malignant Melanoma: a Possible Correlation with Prognosis and Clinical Outcome
Lara Camillo
Università del Piemonte Orientale, Italy
5.10 - 5.15 PM
Title: (FC) Unveiling ODC's Role in KRAS-Driven Lung Cancer: Metabolism, Immunity, and Potential Therapeutic Implications
Chiara Donno
Università del Piemonte Orientale, Italy
5.15 - 5.38 PM
Title: (IL) Immune Response Transcriptome is Unique for each Cancer Nodule in the Prostate Tumor
Dumitru Andrei Iacobas
Prairie View A&M University, USA
5.38 - 5.53 PM
Title: (OC) Comparative Omics and Bioinformatics: Opportunities and Perspectives for Life Sciences and Cancer Biology
Maria Luisa Chiusano
Università degli Studi di Napoli Federico II, Italy
5.53 - 6.16 PM
Title: (IL) Boric Acid Enhances Cisplatin Sensitivity by Disrupting DNA Double-Strand Break Repair in Breast Cancer Stem Cells
Hülyam Kurt
Eskisehir Osmangazi University, Turkey
6.16 - 6.21 PM
Title: (FC) Targeting Integrin β1 to Increase Drug Sensitivity in Triple Negative Breast Cancer
Chiara Mocchetti
Università del Piemonte Orientale, Italy
6.21 - 6.26 PM
Title: (FC) Discovery and Characterization of a Novel Kinase Regulator of the Autophagy Pathway in Pediatric Gliomas
Suheda Duran
Koç University, Turkey
6.26 - 6.31 PM
Title: (FC) Characterizing eNAMPT-Mediated Circulating Tumour Cells Modulation During Breast Cancer Progression
Federica Balestrero
Università del Piemonte Orientale, Italy
6.31 - 6.36 PM
Title: (FC) Exploring the Molecular Mechanisms of Early-Onset Breast Cancer
Federico Tolino
Università del Piemonte Orientale, Italy
6.36 - 6.41 PM
Title: (FC) Characterization of Tumor-Associated Macrophages in Liver-Metastasized Colon Cancer and its Role in Prognosis
Candela Cives-Losada
Università del Piemonte Orientale, Italy
6.41 - 7.11 PM
Title: (KL) Mechanisms and Targets for Obesity-Driven Prostate Cancer Progression
John DiGiovanni
The University of Texas, USA
7.10 – 7.30 PM Award ceremony and Closing ceremony
-Award "Comoli-Ferrari" for Best Young Presenter (delivered by Dr. Paolo Ferrari & Dr. Anastasia Ferrari)
-Closing ceremony
Prof. Dr. John DiGiovanni
Prof. Dr. Devrim Gozuacik
Prof. Dr. Gianluca Gaidano
Prof. Dr. Ciro Isidoro
7.30 - 9.00 PM Farewell party
Social event - Apericena Buffet
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