Monday, May 27th
1.30 – 2.30 PM Registration
2.30 – 3.00 PM Opening ceremony
Greeting of the Authorities
Dr. Alessandro Canelli, Mayor
Prof. Dr. Gian Carlo Avanzi, Rector
Dr. Gianfranco Zulian, Hospital Chief Executive
Prof. Dr. Gianluca Gaidano, Director of School of Medicine
Prof. Dr. Marisa Gariglio, Vice Director of DIMET
Prof. Dr. Ciro Isidoro, Head of the conference
3.00 – 6.15 PM 1st Session Chair: Matteo Donadon - Lucia Anna Stivala
3.00 - 3.30 PM
Title: Increasing Evidence for the Application of FAK1 Inhibitors in Melanoma Therapy (KL)
Daniela De Zio
3.30 - 3.55PM
Title: Evolution of Breast Cancer Biomarkers: from Molecular Pathology to Artificial Intelligence (IL)
Nicola Fusco
3.55 - 4.20 PM
Title: Spatial Resolution of Cellular Senescence Dynamics in Human Colorectal Liver Metastasis (IL)
Francesca Faggioli
4.20 - 4.45 PM
Title: Translational Control of Metabolism Regulates Cancer Progression (IL)
Stefano Biffo
4.45 - 5.00 PM
Title: The Impact of NAMPT/NAD Axis in Metabolic/Translational Reprogramming and Tumor-Host Crosstalk in Metastatic Melanoma (OC)
Valentina Audrito
5.00 - 5.15 PM
Title: Ovarian Cancer Cell-conditioning Medium Promotes Cancer-Associated Fibroblasts Phenoconversion via Glucose-Dependent Inhibition of Autophagy (OC)
Alessandra Ferraresi
5.15 - 5.30 PM
Title: Class II PI3K Mediated Regulation of mTOR in Glutamine Sensing within Pancreatic Cancer (OC)
Maria Chiara De Santis
5.30 - 5.40 PM
Title: Effects of Stilbenes Treatment on the Proliferation and Stemness of Human Lung Cancer Side Population Cells (SC)
Vittoria Livraghi
5.40 - 5.50 PM
Title: Unravelling the Role of miRNAs Differentially Expressed in Thyroid Carcinoma (SC)
Francesca Maria Orlandella
5.50 - 6.00 PM
Title: Exposure to Differentiation Treatment Reduces Pathogenic Traits of a NSCLC Model in vitro (SC)
Alice Grossi
6.00 - 6.10 PM
Title: Exploring the Therapeutic Potential of Erucin, an H2S-Releasing Isothiocyanate, in in Vitro and in Vivo models of Triple-Negative Breast Cancer (SC)
Ivana Bello
6.10 - 6.15 PM
Title: Intestinal Microbiota, Diet, and Obesity Concur in Colorectal Cancer Development (FC)
Marta Potenza
6.15 – 7.30 PM Welcome party
Social event - Aperitivo Buffet
7.30 PM Classical music concert and Apericena buffet (by invitation only)
Social event at Conservatorio "Guido Cantelli"
Tuesday, May 28th
8.30 – 11.00 AM 2nd Session Chair: Arnold Stern - Svetlana Chulkova
8.30 - 8.45 AM
Title: Preclinical Studies Exploring the Effects of Resveratrol-Induced Autophagy on Xenograft Cholangiocarcinogenesis (OC)
Suyanee Thongchot
8.45 - 8.55 AM
Title: Mutational Status of Kappa and Lambda Light Chain Genes Independently Predicts Time to First Treatment in Early-Stage Chronic Lymphocytic Leukemia (SC)
Abel Mehari Sium
8.55 - 9.05 AM
Title: miR-214-Driven Cell Metabolism Rewiring Leads to Melanoma Progression (SC)
Sara Cozzubbo
9.05 - 9.15 AM
Title: Extracellular Nicotinamide Phosphoribosyltransferase (eNAMPT): a Novel Pro-Angiogenic Regulator of Pericytes (SC)
Marianna Moro
9.15 - 9.45 AM
Title: Tumor Reversion as a New Promising Perspective for Cancer Management (KL)
Mariano Bizzarri
9.45 - 10.10 AM
Title: A Novel Role of Autophagy Inhibitor MIR376B in Breast Cancer (IL)
Yunus Akkoc
10.10 - 10.25 AM
Title:The lncRNA PVT1 Cooperates with ERα and EZH2 Inducing a Downregulation of Tumor Suppressor Genes in Hormone-Responsive Breast Cancer (SC)
Viola Melone
10.25 - 10.35 AM
Title: SIRT1 Modulation of p53 and DNA Damage Response in HPV-Associated Cancer Reveals Potential Therapeutic Interventions (SC)
Marta Catozzo
10.35 - 10.45 AM
Title: Nanobiotechnological Engineering of the M13 Bacteriophage for Targeted Photodynamic Cancer Therapy (SC)
Alena Kaltenbrunner
10.45 - 10.55 AM
Title: Integration of 18F-FDG–PET Radiomics with Liquid Biopsy Improves Outcome Prediction in Newly Diagnosed DLBCL Patients (SC)
Mohammad Almasri
10.55 - 11.00 AM
Title: Defining Common Genomic and Transcriptomic Profiles in Richter’s Syndrome Paves the Way for Drug Repurposing Strategies (FC)
Francesco Edoardo Vallono
11.00 – 11.30 AM Coffee break
11.30 AM – 1.30 PM 3rd Session Chair: Ann Zeuner - Riccardo Moia
11.30 AM - 12.00 AM
Title: Clinical Impact of Minimal Residual Disease in follicular and Mantle Cell Lymphoma (KL)
Simone Ferrero
12.00 AM - 12.25 PM
Title: Using VBIM Technique to Discover ARMC4/ODAD2 as a Novel Negative Regulator of NF-KB and a New Tumor Suppressor in Colorectal Cancer (IL)
Tao Lu
12.25 - 12.50 PM
Title: Muscle Heme Metabolism Shapes Metastasis: A New Twist on an Old Story (IL)
Alessio Menga
12.50 - 1.05 PM
Title: N6-Isopentenyladenosine Impairs Mitochondrial Metabolism through Inhibition of EGFR Translocation on Mitochondria in Glioblastoma Cells (OC)
Cristina Pagano
1.05 - 1.15 PM
Title: Prevalence and Clinical Impact of Clonal Hematopoiesis of Indeterminate Potential (CHIP) in Chronic Lymphocytic Leukemia (SC)
Chiara Cosentino
1.15 - 1.25 PM
Title: 3D Genome Organization in Lung Cancer Cells Is Affected by the Chemotherapy Drug Erlotinib (SC)
Guruprasadh Swaminathan
1.25 - 1.30 PM
Title: NOTCH1 Orchestrates Metabolic Reprogramming to Drive Proliferation in a Novel Cellular Model of Chronic Lymphocytic Leukemia (FC)
Silvia Seghezzi
1.30 – 2.30 PM Lunch
2.30 – 7.00 PM 4th Session Chair: Tao Lu - Virginie Sottile
2.30 - 2.35 PM
Title: CTF1 is a novel predictive marker in breast cancer (FC)
Ece Dilege
2.35 - 2.50 PM
Title: Droplet Digital PCR Development to Quantify the DNA Methylation Levels of SEPT9 and SHOX2 in Plasma from Patients with Head and Neck Squamous Cell Carcinoma (OC)
Ilaria Grossi
2.50 - 3.15 PM
Title: Cancer Dormancy: an Evolutionary Conserved Strategy at the Roots of Drug Resistance, Relapse and Metastatization (IL)
Ann Zeuner
3.15- 3.45 PM
Title: Identification of Novel Phytochemical Combinations for Prevention of Prostate Cancer (KL)
John DiGiovanni
3.45 - 4.00 PM
Title: IκBα-Mediated Endothelial Activation Facilitates Lung Cancer Metastasis (OC)
Giovanna Carrà
4.00 - 4.15 PM
Title: Extracellular Nicotinamide Phosphoribosyltransferase (eNAMPT) Modulates the Tumour Microenvironment Toward a more Aggressive Phenotype in Triple Negative Breast Cancer (OC)
Ambra Grolla
4.15 - 4.30 PM
Title: Single-Nuclei Transcriptome Profiling Reveals the Architecture of Tumor-Microenvironment Interface Induced by VEGFA/BRAF Targeting in Murine Melanoma Model (OC)
Sushant Parab
4.30 - 4.40 PM
Title: eNAMPT Increases Breast Cancer Metastasis by Modulating the Epithelial-to-Mesenchymal Transition (SC)
Federica Balestro
4.40 - 4.50 PM
Title: miR-214 Inhibition Reduces Osteosarcoma Progression (OC)
Francesca Orso
4.50 - 5.00 PM
Title: Myo-Inositol Inhibits PI3K Expression in Normal and Cancerous Breast Cells and Modulates Downstream Pro-Oncogenic Pathways (SC)
Alessandro Querqui
5.00 - 5.10 PM
Title: Dissecting the Role of Carbon Monoxide in Chemoresistance (SC)
Giulia Ballerini
5.10 - 5.20 PM
Title: MiR148b Induces Mitochondrial Dysfunction and Affects Melanoma Progression (SC)
Martina Coco
5.20 - 5.30 PM
Title: Integrative Bioinformatics Analysis Reveals the LSD1-ATF4 Axis Governing microRNA Regulatory Networks in Glioblastoma (SC)
Teresa Gravina
5.30 - 5.40 PM
Title: UV-C Irradiation in DDB2PCNA- Cells Determines the Formation of Cellular Clones with Tumorigenic Characteristics (SC)
Anna Tricarico
5.40 - 5.45 PM
Title: Circulating Immune Cells Predict Immunotherapy Benefit in Patients with Triple Negative Breast Cancer: Preliminary Results from the IRIS Study (FC)
Rami Alsati
5.45 - 5.50 PM
Title: STAT3 is Phosphorylated on Ser 727 at the ER by mTOR, then Regulating ER Ca2+Release and Ca2+-Mediated Apoptosis (FC)
Daniele Viavattene
5.50 - 5.55 PM
Title: In vitro Evidence of Cross-Communication between 4T1 Breast Tumor Cells and Adult Neural Progenitor Cells (FC)
Camilla D'Angelo
5.55 - 6.00 PM
Title: A Screening for Atrophy Promoters in Cancer Cell Secretome (FC)
Giada Fregnan
6.00 - 6.05 PM
Title: Synergistic Cancer Effect of ICOS-Fc/Paclitaxel Nanobubbles in Murine Melanoma Models (FC)
Foteini Christaki
6.05 - 6.30 PM
Title: The Role of Bone Marrow B Lymphocytes in the Prognosis of Breast Cancer (IL)
Svetlana Chulkova
6.30 - 7.00PM
Title: “Splice and Conquer”: Targeting the Oncogenic Strategy of UCA1 in Ovarian Cancer (KL)
Danny N. Dhanasekaran
7.00 – 7.15 PM Closing ceremony
Prof. Dr. John DiGiovanni
Prof. Dr. Danny N. Dhanasekaran
Prof. Dr. Gianluca Gaidano
Prof. Dr. Ciro Isidoro
7.15 - 9.30 PM Farewell party
Social event - Apericena Buffet